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1

Novel anticancer agents, kayeassamins C−I from the flower of Kayea assamica of Myanmar

Nwet Nwet Win, Suresh Awale, Hiroyasu Esumi, Yasuhiro Tezuka, Shigetoshi Kadota

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 483 KB

english, 2008

2

Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line

Nguyen, Hai Xuan, Do, Truong Nhat Van, Le, Tho Huu, Nguyen, Mai Thanh Thi, Nguyen, Nhan Trung, Esumi, Hiroyasu, Awale, Suresh

Journal:

Journal of Natural Products

Year:

2016

Language:

english

File:

PDF, 8.18 MB

english, 2016

3

Angelmarin, a novel anti-cancer agent able to eliminate the tolerance of cancer cells to nutrient starvation

Suresh Awale, Eduardo M.N. Nakashima, Surya K. Kalauni, Yasuhiro Tezuka, Yukiko Kurashima, Jie Lu, Hiroyasu Esumi, Shigetoshi Kadota

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

4

Novel anticancer agents, kayeassamins A and B from the flower of Kayea assamica of Myanmar

Nwet Nwet Win, Suresh Awale, Hiroyasu Esumi, Yasuhiro Tezuka, Shigetoshi Kadota

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 417 KB

english, 2008

5

Ketoconazole inhibits lipopolysaccharide-induced activation of the nitric oxide synthase gene in the murine macrophage cell line J774

Adone Baroni, Vincenzo Ruocco, P. De Paolis, Luigi Cicatiello, Hiroyasu Esumi, M. A. Tufano

Journal:

Archives of Dermatological Research

Year:

1999

Language:

english

File:

PDF, 89 KB

english, 1999

6

Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome

Satoshi Fujii, Shuichi Mitsunaga, Manabu Yamazaki, Takahiro Hasebe, Genichiro Ishii, Motohiro Kojima, Taira Kinoshita, Takashi Ueno, Hiroyasu Esumi, Atsushi Ochiai

Journal:

Year:

2008

Language:

english

File:

PDF, 523 KB

english, 2008

7

Involvement of DNA polymerase β in proliferation of rat liver induced by lead nitrate or partial hepatectomy

Marta Menegazzi, Alessandra Carcereri de Prati, Tsutomu Ogura, Amedeo Columbano, Giovanna Maria Ledda-Columbano, Massimo Libonati, Hiroyasu Esumi, Hisanori Suzuki

Journal:

Year:

1992

Language:

english

File:

PDF, 470 KB

english, 1992

8

ARK5 Expression in Colorectal Cancer and Its Implications for Tumor Progression

Gen-ichi Kusakai, Atsushi Suzuki, Tsutomu Ogura, Sin'ichi Miyamoto, Atsushi Ochiai, Michio Kaminishi, Hiroyasu Esumi

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 849 KB

english, 2004

9

Marked nitrosation by stimulation with lipopolysaccharide in ascorbic acid-deficient rats

Kosaka, Hiroaki, Tsuda, Mitsuhiro, Kurashima, Yukiko, Esumi, Hiroyasu, Terada, Nobuyuki, Ito, Yasuhiro, Uozumi, Mitsuro

Journal:

Year:

1990

Language:

english

File:

PDF, 265 KB

english, 1990

10

Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer

Okada, Takuya, Minehira, Daisuke, Takada, Minetatsu, Urata, Hirokazu, Kato, Atsushi, Adachi, Isao, Kurashima, Yukiko, Kaji, Satoshi, Ogura, Tsutomu, Chiba, Shigeki, Esumi, Hiroyasu, Toyooka, Naoki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 843 KB

english, 2016

11

Effect of Systemic L-Arginine Administration on Hemodynamics and Nitric Oxide Release in Man.

HISHIKAWA, Keiichi, NAKAKI, Toshio, TSUDA, Mitsuhiro, ESUMI, Hiroyasu, OHSHIMA, Hiroshi, SUZUKI, Hiromichi, SARUTA, Takao, KATO, Ryuichi

Journal:

Japanese Heart Journal

Year:

1992

File:

PDF, 412 KB

1992

12

Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: Expression and hypoxic regulation

Oleksandr H. Minchenko, Tsutomu Ogura, Iryna L. Opentanova, Dmytro O. Minchenko, Hiroyasu Esumi

Journal:

Molecular and Cellular Biochemistry

Year:

2005

Language:

english

File:

PDF, 476 KB

english, 2005

13

Evidence for a Synergistic Interaction between Cadmium and Endotoxin Toxicity and for Nitric Oxide and Cadmium Displacement of Metals in the Kidney

Soisungwan Satarug, Jason R. Baker, Paul E.B. Reilly, Hiroyasu Esumi, Michael R. Moore

Journal:

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

14

Purification of mouse pepsinogens by pepstatin-affinity chromatography

Hiroyasu Esumi, Shigeaki Sato, Takashi Sugimura, Chie Furihata

Journal:

Year:

1978

Language:

english

File:

PDF, 317 KB

english, 1978

15

Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon

Naoyuki Yamashita, Toshinari Minamoto, Atsushi Ochiai, Masahiko Onda, Hiroyasu Esumi

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 2.45 MB

english, 1995

16

S1606: μ-VOIS, A Novel Three-Dimensional Microstructure Imaging System Based on Optical Coherence Tomography

Kazuhiro Kaneko, Hiroaki Ikematsu, Tomonori Yano, Keiko Minashi, Takashi Kojima, Yasuhiro Oono, Atsushi Ohtsu, Atsushi Ochiai, Hiroyasu Esumi

Journal:

Gastrointestinal Endoscopy

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

17

Effects Of Snark-deficiency On Whole-body Metabolism With High Fat Diet

Ichinoseki-Sekine, Noriko, Naito, Hisashi, Yoshihara, Toshinori, Tsuchihara, Katsuya, Esumi, Hiroyasu

Journal:

Medicine & Science in Sports & Exercise

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

18

Effects of ubiquinone enriched diet on deterioration of mitochondrial respiratory function caused by fried beef derived mutagenic factor in rats

Satoru Sugiyama, Koujirou Yamada, Mika Hayakawa, Hiroyasu Esumi, Takayuki Ozawa

Journal:

Year:

1996

Language:

english

File:

PDF, 543 KB

english, 1996

19

Induction of DNA polymerase β during proliferation of mitogen-stimulated human lymphocytes

Hisanori Suzuki, Marta Menegazzi, Alessandra Carcereri De Prati, Tsutomu Ogura, Hiroyasu Esumi, Akio Matsukage, Massimo Libonati

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 1.31 MB

english, 1991

20

Modification by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) of 3,2′-dimethyl-4-aminobiphenyl (DMAB)-induced rat pancreatic and intestinal tumorigenesis

Kumiko Ogawa, Shougo Iwasaki, Hiroyasu Esumi, Shoji Fukushima, Tomoyuki Shirai

Journal:

Year:

1998

Language:

english

File:

PDF, 117 KB

english, 1998

21

Bioactive Secondary Metabolites from Boesenbergia pandurata of Myanmar and Their Preferential Cytotoxicity against Human Pancreatic Cancer PANC-1 Cell Line in Nutrient-Deprived Medium

Win, Nwet Nwet, Awale, Suresh, Esumi, Hiroyasu, Tezuka, Yasuhiro, Kadota, Shigetoshi

Journal:

Journal of Natural Products

Year:

2007

Language:

english

File:

PDF, 133 KB

english, 2007

22

Effect of docosahexaenoic acid on azoxymethane-induced colon carcinogenesis in rats

Takahashi, Mami, Minamoto, Toshinari, Yamashita, Naoyuki, Kato, Toshio, Yazawa, Kazunaga, Esumi, Hiroyasu

Journal:

Year:

1994

Language:

english

File:

PDF, 687 KB

english, 1994

23

The examination of coexistence of MnSOD, NOS, calbindin and parvalbumin in the rat hippocampus

Matsui, Tokuzo, Takagi, Hiroshi, Esumi, Hiroyasu

Journal:

Neuroscience Research Supplements

Year:

1994

Language:

english

File:

PDF, 108 KB

english, 1994

24

Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways

Yamashita, Teruhito, Uehara, Shunsuke, Udagawa, Nobuyuki, Li, Feng, Kadota, Shigetoshi, Esumi, Hiroyasu, Kobayashi, Yasuhiro, Takahashi, Naoyuki, Costa-Rodrigues, João

Journal:

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

25

Measurement and verification of positron emitter nuclei generated at each treatment site by target nuclear fragment reactions in proton therapy

Miyatake, Aya, Nishio, Teiji, Ogino, Takashi, Saijo, Nagahiro, Esumi, Hiroyasu, Uesaka, Mitsuru

Journal:

Medical Physics

Year:

2010

Language:

english

File:

PDF, 460 KB

english, 2010

26

Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide

Kimura, Hideo, Weisz, Alessandro, Kurashima, Yukiko, Hashimoto, Kouichi, Ogura, Tsutomu, D'Acquisto, Fulvio, Addeo, Raffaelo, Makuuchi, Masatoshi, Esumi, Hiroyasu

Journal:

Year:

2000

File:

PDF, 317 KB

2000

27

Kigamicins, Novel Antitumor Antibiotics. Part 2. Structure Determination.

Setsuko Kunimoto, Tetsuya Someno, Yohko Yamazaki, Jie Lu, Hiroyasu Esumi, Hiroshi Naganawa

Journal:

Year:

2004

File:

PDF, 50 KB

2004

28

Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs

Hiroko Onozuka, Katsuya Tsuchihara, Hiroyasu Esumi

Journal:

Year:

2011

Language:

english

File:

PDF, 536 KB

english, 2011

29

Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells

Chin, Keisho, Kurashima, Yukiko, Ogura, Tsutomu, Tajiri, Hisao, Yoshida, Shigeaki, Esumi, Hiroyasu

Journal:

Year:

1997

Language:

english

File:

PDF, 369 KB

english, 1997

30

Cloning and functional expression of poly(ADP-ribose) polymerase cDNA from Sarcophaga peregrina

Mitsuko MASUTANI, Tadashige NOZAKI, Yoshiaki HITOMI, Miyoko IKEJIMA, Koichi NAGASAKI, Alessandra Carcereri DE PRATI, Shoichi KURATA, Shunji NATORI, Takashi SUGIMURA, Hiroyasu ESUMI

Journal:

Year:

1994

Language:

english

File:

PDF, 961 KB

english, 1994

31

Turnover of serum proteins in rats with analbuminemia

Hiroyasu Esumi, Shigeaki Sato, Mitsuko Okui, Takashi Sugimura, Sumi Nagase

Journal:

Biochemical and Biophysical Research Communications

Year:

1979

Language:

english

File:

PDF, 1.11 MB

english, 1979

32

Sympathetic preganglionic neurons contain nitric oxide synthase and project to the superior cervical ganglion: Combined application of retrograde neuronal tracer and NADPH-diaphorase histochemistry

Okamura, Hitoshi, Umehara, Kaori, Tadaki, Nobukatsu, Hisa, Yasuo, Esumi, Hiroyasu, Ibata, Yasuhiko

Journal:

Brain Research Bulletin

Year:

1995

Language:

english

File:

PDF, 471 KB

english, 1995

33

[Part 1: Biological Sciences] || A Seven-Base-Pair Deletion in an Intron of the Albumin Gene of Analbuminemic Rats

Hiroyasu Esumi, Yuri Takahashi, Shigeaki Sato, Sumi Nagase and Takashi Sugimura

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.24 MB

english, 1983

34

High frequency and low specificity of ras gene mutations in rat Zymbal's gland tumors induced by 2-amino-3-methylimidazo[4, 5- f ]quinoline

Takahashi, Mami, Minamoto, Toshinari, Sugimura, Tokashi, Esumi, Hiroyasu

Journal:

Year:

1993

Language:

english

File:

PDF, 2.38 MB

english, 1993

35

Implication of nitric oxide synthase in carcinogenesis: analysis of the human inducible nitric oxide synthase gene

Esumi, Hiroyasu, Ogura, Tsutomu, Kurashima, Yukiko, Adachi, Hiroko, Hokari, Atsushi, Weisz, Alessandro

Journal:

Pharmacogenetics

Year:

1995

File:

PDF, 442 KB

1995

36

Regulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunit

TOMITSUKA, Eriko, KITA, Kiyoshi, ESUMI, Hiroyasu

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Year:

2009

Language:

english

File:

PDF, 789 KB

english, 2009

37

Kigamicins, Novel Antitumor Antibiotics: I. Taxonomy, Isolation, Physico-chemical Properties and Biological Activities

KUNIMOTO, SETSUKO, LU, JIE, ESUMI, HIROYASU, YAMAZAKI, YOHKO, KINOSHITA, NAOKO, HONMA, YOSHIKO, HAMADA, MASA, OHSONO, MICHIYO, ISHIZUKA, MASAAKI, TAKEUCHI, TOMIO

Journal:

The Journal of Antibiotics

Year:

2003

Language:

english

File:

PDF, 1.31 MB

english, 2003

38

Infrequent somatic mutation of the adenomatous polyposis coli gene in aberrant crypt foci of human colon tissue

Kazuhiko Otori, Motoko Konishi, Kenji Sugiyama, Takahiro Hasebe, Tadakazu Shimoda, Rei Kikuchi-Yanoshita, Kiyoshi Mukai, Shoji Fukushima, Michiko Miyaki, Hiroyasu Esumi

Journal:

Year:

1998

Language:

english

File:

PDF, 99 KB

english, 1998

39

Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population

Yuji Minegishi, Hiromasa Tsukino, Manabu Muto, Koichi Goto, Akihiko Gemma, Shoichiro Tsugane, Shoji Kudoh, Yutaka Nishiwaki, Hiroyasu Esumi

Journal:

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

40

Detection of serum nitrite and nitrate in primary biliary cirrhosis: Possible role of nitric oxide in bile duct injury

ATSUSHI HOKARI, MIKIO ZENIYA, HIROYASU ESUMI, TOMONOBU KAWABE, M ERIC GERSHWIN, GOTARO TODA

Journal:

Journal of Gastroenterology and Hepatology

Year:

2002

Language:

english

File:

PDF, 875 KB

english, 2002

41

Suppression of Gl Arrest and Enhancement of G2 Arrest by Inhibitors of Poly(ADP-ribose) Polymerase: Possible Involvement of Poly(ADP-ribosyl)ation in Cell Cycle Arrest Following γ-Irradiation

Tadashige Nozaki, Mitsuko Masutani, Tetsuya Akagawa, Takashi Sugimura, Hiroyasu Esumi

Journal:

Year:

1994

File:

PDF, 290 KB

1994

42

Protective effect of prostaglandin E1 against ischemia/reperfusion-induced liver injury: results of a prospective, randomized study in cirrhotic patients undergoing subsegmentectomy

Yasuhiko Sugawara, Keiichi Kubota, Tsutomu Ogura, Hiroyasu Esumi, Kazuto Inoue, Tadotoshi Takayama, Masatoshi Makuuchi

Journal:

Journal of Hepatology

Year:

1998

Language:

english

File:

PDF, 191 KB

english, 1998

43

Sharper Image of Breast Cancer Cells and Stroma in Dense Breast Using Thinner Angular Filter under X-Ray Dark-Field Imaging

Ando, Masami, Sugiyama, Hiroshi, Ichihara, Shu, Endo, Tokiko, Bando, Hiroko, Yamasaki, Katsuhito, Ohbayashi, Chiho, Chikaura, Yoshinori, Esumi, Hiroyasu, Maksimenko, Anton

Journal:

Japanese Journal of Applied Physics

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

44

Nitric oxide synthase-immunoreactive nerve fibers in the nasal mucosa of the rat

Toyoyuki Hanazawa, Akiyoshi Konno, Toshio Kaneko, Koichi Tanaka, Hiroshi Ohshima, Hiroyasu Esumi, Tanemichi Chiba

Journal:

Year:

1994

Language:

english

File:

PDF, 1.02 MB

english, 1994

45

Lineage and Clonal Development of Gastric Glands

Sachiyo Nomura, Hiroyasu Esumi, Christopher Job, Seong-Seng Tan

Journal:

Developmental Biology

Year:

1998

Language:

english

File:

PDF, 23.72 MB

english, 1998

46

Supplement 6: Carcinogenic and Mutagenic N-Substituted Aryl Compounds || The Role of Fat and Calcium in the Production of Foci of Aberrant Crypts in the Colon of Rats Fed 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]-Pyridine

John H. Weisburger, Joanne Braley, Joel Reinhardt, Cesar Aliaga, Abraham Rivenson, Gordon C. Hard, Xue-Ming Zhang, Mami Takahashi, Hiroyasu Esumi and Takashi Sugimura

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 635 KB

english, 1994

47

Formation of thiazolidine-4-carboxyiic acid (thioproline), an effective nitrite-trapping agent in human body, in Parkia speciosa seeds and other edible leguminous seeds in Thailand

Wallie Suvachittanont, Yukiko Kurashima, Hiroyasu Esumi, Mitsuhiro Tsuda

Journal:

Year:

1996

Language:

english

File:

PDF, 647 KB

english, 1996

48

Expression of Two Types of Nitric Oxide Synthase mRNA in Human Neuroblastoma Cell Lines

Hironori Fujisawa, Tsutomu Ogura, Yukiko Kurashima, Takeshi Yokoyama, Junkoh Yamashita, Hiroyasu Esumi

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 812 KB

english, 1994

49

Preliminary Study of Percutaneous Alcohol Injection into the Lung

Kenji Suzuki, Noriyuki Moriyama, Tomoyuki Yokose, Yoshihiro Nakaya, Toshihiro Ishihara, Seiji Niho, Kanji Nagai, Hiroyasu Esumi

Journal:

Year:

1998

Language:

english

File:

PDF, 820 KB

english, 1998

50

Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation

Kato, Kazuyoshi, Ogura, Tsutomu, Kishimoto, Atsuhiro, Minegishi, Yuji, Nakajima, Nobuyuki, Miyazaki, Masaru, Esumi, Hiroyasu

Journal:

Year:

2002

Language:

english

File:

PDF, 283 KB

english, 2002

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